WebThe concentration of chromogranin A was measured in serum with a commercial solid-phase two-site immunoradiometric assay. Elevated serum levels of chromogranin A were found in 32 of 79 patients (43%). Levels over 600 ng/ml were present in 7 of 76 patients (9.2%), all of whom had very high serum levels of alpha-fetoprotein. WebWe report the case of a 50-year-old female patient who presented with symptoms suggestive of a serotonin- secreting neuroendocrine neoplasm. In addition, her serum chromogranin A (CA) level was elevated by more than 8-fold. Methods We present a case report with review of the relevant literature. Results
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Web18 de jan. de 2024 · A gastrinoma is a pancreas tumor that causes large amounts of gastrin and gastric acid to be released. It can lead to Zollinger-Ellison syndrome, a disease with very high gastrin levels, stomach and small intestine ulcers, and diarrhea. People with this disease can have gastrin levels as high as 2000 pg/ml [ 14, 17 ]. WebSerum CGA measurements are particularly suited for diagnosing hindgut tumors, being elevated in nearly all cases, even though serotonin and 5-HIAA are often normal. CGA is also elevated in 80% to 90% of patients with symptomatic foregut and midgut tumors. ina tc1423
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WebTo investigate serum gastrin and CgA levels in dyspeptic patients during continuous medium- (6 weeks to 1 year), or long-term (1-8 years) gastric acid suppressive therapy. Patients and methods: Omeprazole doses ranged from 20 mg to 80 mg daily and ranitidine from 150 mg to 450 mg daily. Web24 de abr. de 2024 · "CgA levels can be elevated in a range of health conditions other than neuroendocrine tumors. For example, CgA levels may increase in people with irritable bowel disease, chronic hepatitis, liver failure, inflammatory diseases, and renal failure. Several medications can also cause an elevation in CgA levels. Web13 de abr. de 2024 · In cases of primary neuroendocrine malignancies, the use of [18F]FDG for imaging high-grade P-NECs and radiolabeled somatostatin-analogues for imaging well-differentiated P-NETs is recommended. ... may be stable or only moderately elevated, while levels of chromogranin A (a neuroendocrine secretory protein) may be rising [28,29,30]. in a factory women are 35%